Bioorganic and medicinal chemistry (Online)
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Discovery and structure-activity relationship of Morita-Baylis-Hillman adducts as larvicides against dengue mosquito vector, Aedes aegypti (Diptera: Culicidae).
1:1-9.
2023-01-01
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Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors.
78:117132.
2023-01-01
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The protein disulfide isomerase inhibitor 3-methyltoxoflavin inhibits Chikungunya virus.
83:117239-117251.
2023-01-01
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Current Trends in Designing Antiviral Agents Against Emerging and Re-Emerging RNA Viruses.
62:116741-116742.
2022-01-01
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Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata.
63:116749-116762.
2022-01-01
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Evaluation of crotamine based probes as intracellular targeted contrast agents for magnetic resonance imaging.
69:116863.
2022-01-01
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Protective immunity triggered by ectonucleoside triphosphate diphosphohydrolase-based biopharmaceuticals attenuates cardiac parasitism and prevents mortality in Trypanosoma cruzi infection.
1:1-10.
2022-01-01
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Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer?s disease.
71:116952-11.
2022-01-01
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Synthesis and medicinal chemistry of tetronamides: Promising agrochemicals and antitumoral compounds.
67:116815.
2022-01-01
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The 2022 Monkeypox outbreak: How the medicinal chemistry could help us?.
73:1-3.
2022-01-01
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A styrylpyrone dimer isolated from Aniba heringeri causes apoptosis in MDA-MB-231 triple-negative breast cancer cells.
32:115994-X.
2021-01-01
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Anti-HER2 monoclonal antibody based-radioimmunoconjugates: assessment of the chelating agent influence.
115996:115996.
2021-01-01
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Antileishmanial macrolides from ant-associated Streptomyces sp. ISID311.
32:116016.
2021-01-01
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Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis.
12:116506-116530.
2021-01-01
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Antiviral fungal metabolites and some insights into their contribution to the current COVID-19 pandemic.
46:116366.
2021-01-01
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Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases.
40:116213-116213.
2021-01-01
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Cysteine proteases as potential targets for anti-trypanosomatid drug discovery.
46:116365.
2021-01-01
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Discovery, development, chemical diversity and design of isoxazoline-based insecticides.
30:115934.
2021-01-01
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In vitro activity of N-phenyl-1,10-phenanthroline-2-amines against tachyzoites and bradyzoites of Toxoplasma gondii.
50:116467.
2021-01-01
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Larvicidal activity and in silico studies of cinnamic acid derivatives against Aedes aegypti (Diptera: Culicidae).
44:116299-116300.
2021-01-01
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New FDA oncology small molecule drugs approvals in 2020: Mechanism of action and clinical applications.
46:116340.
2021-01-01
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Nitrile-based peptoids as cysteine protease inhibitors.
41:116211.
2021-01-01
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Novel arylcarbamate-N-acylhydrazones derivatives as promising BuChE inhibitors: Design, synthesis, molecular modeling and biological evaluation.
00:115991.
2021-01-01
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Ruthenium(II)- and Palladium(II)-catalyzed position-divergent C H oxygenations of arylated quinones: Identification of hydroxylated quinonoid compounds with potent trypanocidal activity.
40:116164-xx-xx.
2021-01-01
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Structure-Activity Relationship and Mechanistic Studies for a Series of Cinnamyl Hydroxamate Histone Deacetylase Inhibitors.
35:116085-x.
2021-01-01
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Synthesis, antitumor activity and in silico analyses of amino acid derivatives of artepillin C, drupanin and baccharin from green propolis.
47:116372-116385.
2021-01-01
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Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer’s disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation.
28:115470.
2020-01-01
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Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7.
28:115756.
2020-01-01
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Antimalarial and anti-inflammatory activities of new chloroquine and primaquine hybrids: targeting the blockade of malaria parasite transmission.
28:115832-115846.
2020-01-01
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COVID-19 therapy: What weapons do we bring into battle?.
165:115757-26.
2020-01-01
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Crystal structure of Leishmania mexicana cysteine protease B in complex with a highly potent azadipeptide nitrile inhibitor.
001:115743.
2020-01-01
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Cytotoxicity of 4-substituted quinoline derivatives: Anticancer and antileishmanial potential.
28:115511.
2020-01-01
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Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors.
28:115600-115610.
2020-01-01
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Design, synthesis and stepwise optimization of nitrile-based inhibitors of cathepsins B and L.
29:115827.
2020-01-01
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Discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (HKT) from Aedes aegypti.
28:1-13.
2020-01-01
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Discovery of thienothiazolocarboxamide analogues as novel anti-tubercular agent.
28:115797.
2020-01-01
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Druggable targets from coronaviruses for designing new antiviral drugs.
28:115745-115767.
2020-01-01
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Efficient synthesis and antitumor evaluation of 4-aminomethyl-N-arylpyrazoles: Discovery of potent and selective agents for ovarian cancer.
29:115835-115849.
2020-01-01
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Green asymmetric synthesis of epoxypeptidomimetics and evaluation as human cathepsin K inhibitors.
28:115597-x.
2020-01-01
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Mangiferin: A promising natural xanthone from Mangifera indica for the control of acyclovir - resistant herpes simplex virus 1 infection.
28:1-6.
2020-01-01
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New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment.
28:115305.
2020-01-01
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Non-cytotoxic 1,2,3-triazole tethered fused heterocyclic ring derivatives display Tax protein inhibition and impair HTLV-1 infected cells.
1:115746.
2020-01-01
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Novel indol-3-yl-thiosemicarbazone derivatives: obtaining, evaluation of in vivo leishmanicidal activity and ultrastructural studies.
315:108899.
2020-01-01
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Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands - Functional characterization and modeling studies on H3 and H4 receptors.
30:115924.
2020-01-01
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Pegylated catalase as a potential alternative to treat vitiligo and UV induced skin damage.
30:115933.
2020-01-01
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Sequential dual site-selective protein labelling enabled by lysine modification.
28:115783.
2020-01-01
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Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2-+-2-+-2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi.
28:115565.
2020-01-01
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Synthesis and biological evaluation of new antioxidant and antiproliferative chalcogenobiotin derivatives for bladder carcinoma treatment.
28:115423-115434.
2020-01-01
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Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity.
1:115549.
2020-01-01
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Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies.
28:115855-115866.
2020-01-01
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