Bioorganic and medicinal chemistry letters (Online)

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Structure-Activity Relationship of Dibenzylideneacetone Analogs Against the Neglected Disease Pathogen, Trypanosoma brucei. 1:129123-1. 2023-01-01
Structure-activity relationship study of antitrypanosomal analogues of gibbilimbol B using multivariate analysis and computation-aided drug design. 83:129190. 2023-01-01
Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation. 57:128498. 2022-01-01
Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. 60:128588. 2022-01-01
Discovery of novel benzothiophene derivatives as potent and narrow spectrum inhibitors of DYRK1A and DYRK1B. 68:128764. 2022-01-01
Nitro compounds against trypanosomatidae parasites: Heroes or villains?. 1:128930. 2022-01-01
2,2,2-trifluoro-1-(1,4,5,6-tetrahydropyridin-3-yl)ethanone derivative as efflux pump inhibitor in Mycobacterium tuberculosis. 42:128088. 2021-01-01
A late-stage diversification via Heck-Matsuda arylation: Straightforward synthesis and cytotoxic/antiproliferative profiling of novel aryl-labdane-type derivatives. 52:128393-128393. 2021-01-01
Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. 47:128192. 2021-01-01
Design, structure-activity relationship study and biological evaluation of the thieno[3,2-c]isoquinoline scaffold as a potential anti-cancer agent. 52:128327. 2021-01-01
Evaluation of Elaiophylin extracted from Streptomyces hygroscopicus as a potential inhibitor of the NorA efflux protein in Staphylococcus aureus: An in vitro and in silico approach. 50:128334-128341. 2021-01-01
In vitro anti-Leishmania activity and molecular docking of spiro-acridine compounds as potential multitarget agents against Leishmania infantum. 49:128289. 2021-01-01
L-hypaphorine and D-hypaphorine: Specific Antiacetylcholinesterase Activity in Rat Brain Tissue. 47:128206. 2021-01-01
Synthesis Of Pyrazoline Fatty Chain Derivatives And Its Effects On Melanoma Cells. 41:127988. 2021-01-01
Synthesis, docking, machine learning and antiproliferative activity of the 6-ferrocene/heterocycle-2-aminopyrimidine and 5-ferrocene-1H-Pyrazole derivatives obtained by microwave-assisted Atwal reaction as potential anticancer agents. 35:128240. 2021-01-01
Synthetic enamine naphthoquinone derived from lawsone as cytotoxic agents assessed by in vitro and in silico evaluations. 1:128419. 2021-01-01
THC shows activity against cultured Plasmodium falciparum. 54:128442. 2021-01-01
2H-1,2,3-Triazole-chalcones as novel cytotoxic agents against prostate cancer. 30:127454. 2020-01-01
A chalcone derivative binds a putative allosteric site of YopH: inhibition of a virulence factor of Yersinia. 30:127350. 2020-01-01
DNA aptamers selection for carcinoembryonic antigen (CEA). 30:127278. 2020-01-01
Development of 2-(4-pyridyl)-benzimidazoles as PKN2 chemical tools to probe cancer. 1:127040. 2020-01-01
Evaluation of the effect of synthetic compounds derived from azidothymidine on MDA-MB-231 type breast cancer cells. 30:127365. 2020-01-01
Generation of recombinant antibodies against human tissue kallikrein 7 to treat skin diseases. 30:127626. 2020-01-01
Inhibition of the NorA Efflux Pump of S. aureus by (Z)-5-(4-Fluorobenzylidene)-Imidazolidines. 127:127670. 2020-01-01
N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization. 30:127420-6. 2020-01-01
Nanoencapsulation of triterpene 3β,6β,16β-trihydroxylup-20(29)-ene from Combretum leprosum as strategy to improve its cytotoxicity against cancer cell lines. 30:127469. 2020-01-01
Quinolone-N-Acylhydrazone Hybrids as Potent Zika and Chikungunya Virus Inhibitors. 15:126881-126884. 2020-01-01
Structural investigation on thiazolo[5,4-d]pyrimidines to obtain dual-acting blockers of CD73 and adenosine A2A receptor as potential antitumor agents. 30:127067. 2020-01-01
Structure-activity relationship of 4-azaindole-2-piperidine derivatives as agents against Trypanosoma cruzi. 30:126779. 2020-01-01
Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design. 30:127349-127442. 2020-01-01
Synthesis and Matched Molecular Pair Analysis of Covalent Reversible Inhibitors of the Cysteine Protease CPB. 30:127439-6. 2020-01-01
Synthesis and antifungal activity of new hybrids pyrimido[4,5-d]pyridazinone-N-acylhydrazones. 30:127244. 2020-01-01
Synthesis and cytotoxicity evaluation of glycosidic derivatives of lawsone against breast cancer cell lines. 30:126817. 2020-01-01
Synthesis of PJOV56, a new quinoxalinyl-hydrazone derivative able to induce autophagy and apoptosis in colorectal cancer cells, and related compounds. 30:126851-126851. 2020-01-01

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