European journal of medicinal chemistry
-
- Visão geral
-
- Metrics
-
- Identidade
-
- Ver todos
-
Visão geral
Qualis
código do país
tipo
publicação venue de
-
1,3-Thiazole derivatives as privileged structures for anti-Trypanosoma cruzi activity: Rational design, synthesis, in silico and in vitro studies.
115508:115508-11.
2023-01-01
-
Biological activity of 1,2,3-triazole-2-amino-1,4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control.
23:1-14.
2023-01-01
-
Computer-Aided drug design of new 2-amino-thiophene derivatives as anti-leishmanial agents.
2023:115223.
2023-01-01
-
Design and synthesis of new 1,2,3-triazoles derived from eugenol and analogues with in vitro and in vivo activity against Trypanosoma cruzi.
258:115622.
2023-01-01
-
Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituded isoxazole compounds based on benznidazole.
-:115451.
2023-01-01
-
Design, synthesis, antiviral evaluation, and In silico studies of acrylamides targeting nsP2 from Chikungunya virus.
258:115572.
2023-01-01
-
Development of isoselenazolium chlorides as selective pyruvate kinase isoform M2 inhibitors.
257:115504.
2023-01-01
-
Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases.
1:115550-115560.
2023-01-01
-
Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for Chagas disease.
246:114925.
2023-01-01
-
Hit-to-lead optimization of a pyrazinylpiperazine series against Leishmania infantum and Leishmania braziliensis.
256:115445.
2023-01-01
-
Immunosuppressive effects of new thiophene-based KV1.3 inhibitors.
258:115561.
2023-01-01
-
In vitro bioevaluation and docking study of dihydrosphingosine and ethambutol analogues against sensitive and multi-drug resistant Mycobacterium tuberculosis.
115579:1-115579.
2023-01-01
-
New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis.
256:115436-x.
2023-01-01
-
Structural design, synthesis, and anti-Trypanosomatidae profile of new Pyridyl-thiazolidinones.
254:115310-12.
2023-01-01
-
Structure-based discovery of novel cruzain inhibitors with distinct trypanocidal activity profiles.
.:115498-..
2023-01-01
-
Synthesis of cannabidiol-based compounds as ACE2 inhibitors with potential application in the treatment of COVID-19.
260:115760.
2023-01-01
-
Toward anthelmintic drug candidates for toxocariasis: Challenges and recent developments.
251:115268.
2023-01-01
-
Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators.
250:115177.
2023-01-01
-
Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.
234:114270.
2022-01-01
-
Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents.
238:114408.
2022-01-01
-
Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity.
235:114234.
2022-01-01
-
Discovery of 3H-pyrrolo[2,3-c]quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzyme.
232:114206.
2022-01-01
-
From rational design to serendipity: Discovery of novel thiosemicarbazones as potent trypanocidal compounds.
.:114876--.
2022-01-01
-
Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.
xx:114421.
2022-01-01
-
Identification of inhibitors as drug candidates against Chagas disease.
248:115074.
2022-01-01
-
Identification of non-ATP-competitive α-carboline inhibitors of the anaplastic lymphoma kinase.
238:114488.
2022-01-01
-
N-modification of 7-Deazapurine nucleoside analogues as Anti-Trypanosoma cruzi and anti-Leishmania agents: Structure-activity relationship exploration and In vivo evaluation.
1:114165.
2022-01-01
-
N6-modification of 7-Deazapurine nucleoside analogues as Anti-Trypanosoma cruzi and anti-Leishmania agents: Structure-activity relationship exploration and In vivo evaluation.
231:12.
2022-01-01
-
New ruthenium complexes containing salicylic acid and derivatives induce triple-negative tumor cell death via the intrinsic apoptotic pathway.
243:114772.
2022-01-01
-
Novel 4-aminoquinolines: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase, antitubercular activity, SAR, and preclinical evaluation.
00:114908-21.
2022-01-01
-
Pharmaceutical nanotechnology: Antimicrobial peptides as potential new drugs against WHO list of critical, high, and medium priority bacteria.
241:114640-114658.
2022-01-01
-
Rational design of a trypanocidal peptide derived from Dinoponera quadriceps venom.
*:114624-114624.
2022-01-01
-
Synthesis and investigation of the trypanocidal potential of novel 1,2,3-triazole-selenide hybrids.
1:114687.
2022-01-01
-
Tapping into the antitubercular potential of 2,5-dimethylpyrroles: A structure-activity relationship interrogation.
237:114404.
2022-01-01
-
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
.:..
2022-01-01
-
Targeting ecto-5--nucleotidase: A comprehensive review into small molecule inhibitors and expression modulators.
1:115052.
2022-01-01
-
Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance.
240:114571.
2022-01-01
-
Further investigation of harmicines as novel antiplasmodial agents: Synthesis, structure-activity relationship and insight into the mechanism of action.
224:113687.
2021-01-01
-
HIV Latency Reversal Agents: a potential path for functional cure?.
213:113213.
2021-01-01
-
In vitro and in vivo antiplasmodial activity of novel quinoline derivative compounds by molecular hybridization.
215:113271.
2021-01-01
-
Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
224:1-113719.
2021-01-01
-
Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors.
209:112887.
2021-01-01
-
Parasitological profiling shows 4(1H)-quinolone derivatives as new lead candidates for malaria.
3:100012-16.
2021-01-01
-
Recent Advances in Drug Discovery Against Mycobacterium tuberculosis: Metal-based Complexes.
214:113166.
2021-01-01
-
Ruthenium complexes show promise when submitted to toxicological safety tests using alternative methodologies.
216:001-009.
2021-01-01
-
Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27.
225:113777.
2021-01-01
-
Synthesis of alkynylated 1,2,4-oxadiazole/1,2,3-1H-triazole glycoconjugates: Discovering new compounds for use in chemotherapy against lung carcinoma and Mycobacterium tuberculosis.
1:113472.
2021-01-01
-
Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2.
211:113017.
2021-01-01
-
β-lactam antibiotics: An overview from a medicinal chemistry perspective.
208:112829.
2020-01-01
-
A greener protocol for the synthesis of phosphorochalcogenoates: Antioxidant and free radical scavenging activities.
213:113052.
2020-01-01
-
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid.
209:112919-112939.
2020-01-01
-
Anti-tubercular profile of new selenium-menadione conjugates against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain and multidrug-resistant clinical isolates.
209:112859-112859.
2020-01-01
-
C6-O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents.
188:112018.
2020-01-01
-
Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules.
192:112185.
2020-01-01
-
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
-:112941.
2020-01-01
-
Design, synthesis, and biodistribution studies of new analogues of marine alkaloids: Potent in vitro and in vivo fungicidal agents against Candida spp..
1:1-113060.
2020-01-01
-
Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents.
192:112179-112188.
2020-01-01
-
Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors.
194:112255.
2020-01-01
-
Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids.
1:112418.
2020-01-01
-
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
204:112492.
2020-01-01
-
Efficient identification of novel anti-glioma lead compounds by machine learning models.
189:111981-111995.
2020-01-01
-
Harmicines − harmine and cinnamic acid hybrids as novel antiplasmodial hits.
187:111927.
2020-01-01
-
NATURAL AND SYNTHETIC COUMARINS AS ANTILEISHMANIAL AGENTS: A REVIEW.
203:112514.
2020-01-01
-
Natural heat shock protein 90 inhibitors in cancer and inflammation.
189:112063.
2020-01-01
-
New activators of eIF2α Kinase Heme-Regulated Inhibitor (HRI) with improved biophysical properties.
187:111973.
2020-01-01
-
Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities.
186:111887-111894.
2020-01-01
-
Synthesis and anti-Mycobacterium tuberculosis activity of imide-β-carboline and carbomethoxy-β-carboline derivatives.
187:111935-..
2020-01-01
-
Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6.
192:112187.
2020-01-01
-
The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure.
212:113123.
2020-01-01
tem uma área de assunto
publisher
is open access
-
False
invalid format
is in DOAJ
-
False
invalid format
Metrics
2 year mean citedness
H index
i10 index
Identidade
ISSN-L
openalex identifier
-
https://openalex.org/S4210169613
International Standard Serial Number (ISSN)