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João Henrique Picado Madalena Santos

João H. P. M. Santos was born in Ílhavo, Aveiro in 1991. He got his degree in Biotechnology at the University of Aveiro in 2012, as well as his Master Degree in Industrial and Environmental Biotechnology in 2014. In his MSc degree, he conducted a 7-month period of exchange, funded by the Santander-Universities Scholarship Programme, which enabled him to develop the project of Master's thesis at the Laboratory of Pharmaceutical Biotechnology, in the Faculty of Pharmaceutical Sciences of the University of São Paulo, Brazil. He was the first study to establish and conclude a Joint PhD between the University of Aveiro and University of São Paulo Bioengineering in the Bioengineering field founded by the Portuguese Foundation for Science and Technology. He worked as a Researcher for a PROVE IT project for UATEC (Technology Transference), Aveiro University. He was a postdoctoral researcher at Nanobio Lab in the Department of Biochemical and Pharmaceutical Technology of São Paulo University funded by FAPESP (2018/25994-2). He was also an Invited Researcher at IPT (Institute of Technological Research). Current research interests: - Develop of biobetters: improved protein-based biopharmaceuticals by PEGylation; - Downstream processing: aqueous biphasic systems, ultrafiltration, chromatography, and precipitation; - Biotechnological production of biomolecules (from upstream to downstream); - Use of alternative sustainable solvents in upstream & downstream processing: ionic liquids and deep eutectic solvents; - Microfluidics. Currently João is an Associate Professor PART at FCF-USP. Author and co-author of 29 articles in international peer-reviewed multidisciplinary high impact journals (+300 citations, h-index 11), numerous presentations (oral and poster) in national and international conferences; peer reviewer. Official participation in 3 FCT and 3 FAPESP research projects, collaborator in many others.
Possui graduação em Biotecnologia pela Universidade de Aveiro (2012), mestrado na mesma universidade em Biotecnologia ramo Industrial e Ambiental (2014) e doutorado em regime de duplo em Engenharia Química - especialização Bioengenharia entre as Universidade de Aveiro e a Universidade de São Paulo (2019). Pesquisador pós-doutorado FAPESP (2018/25994-2) no laboratório Nanobio (FCF-USP) e pesquisador visitante no IPT. Atualmente é professor colaborador PART na Faculdade de Ciências Farmacêuticas da USP. Tem experiência nas áreas de Biotecnologia, Nanobiotecnologia, Engenharia Química, Alimentar e Ambiental. Os seus principais interesses de investigação são o desenvolvimento de plataformas de novas purificação usando sistemas aquosos bifásicos, tecnologia de solventes alternativos (ex: líquidos iônicos, copolímeros, polímeros biodegradáveis), PEGuilação de proteínas e processos downstream para a purificação de biomoléculas.

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